If a person has a suspected opioid overdose and is unresponsive, what should you do first?

In the case of a suspected opioid overdose where the individual is unresponsive, the most critical first step is to ensure that emergency medical assistance is on the way. In this scenario, calling 9-1-1 is the appropriate first action. This alerts professionals who can provide advanced care and resources that are necessary for the situation, such as administration of naloxone (an opioid antagonist) or advanced airway management if needed.

Monitoring the person's breathing is also important, but it comes after alerting emergency services, as the person may require immediate emergency intervention based on their level of responsiveness and vital signs. Beginning CPR as the first step is not advisable unless the person shows signs of cardiac arrest. Administering sugar is unrelated to an opioid overdose and doesn't address the immediate danger posed by the opioid in the system.

Thus, the first and urgent action should always be calling for professional help to ensure that the person receives the correct medical assistance as quickly as possible.